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KMID : 1037020160050020096
Medical Lasers; Engineering, Basic Research, and Clinical Application
2016 Volume.5 No. 2 p.96 ~ p.100
Improvement of Lax Skin Using a High-Pressure Pneumatic Dermal Delivery System
Moon Ik-Jun

Yu Ji-Su
Choi Won-Ah
Noh Tai-Kyung
Lee Woo-Jin
Chang Sung-Eun
Lee Mi-Woo
Choi Jee-Ho
Won Chong-Hyun
Kim Jie-Hoon
Abstract
Background and Objectives : The high-pressure pneumatic delivery system utilizes an ejection of high-pressure gas delivering desired substances into the subcutaneous tissue and subcutaneous musculoaponeurotic layer.

Materials and Methods : To assess the efficacy and safety of the system, a split-face study was performed. We enrolled18 Asian subjects. Multiple 20%-glucose injections were administered to the temporal area using the high-pressure pneumatic delivery system. Clinical photographs were obtained at baseline and 2 weeks, 1 month, 2 months, and 3 months after injections. A five-point grading scale was used by to evaluate the results. To evaluate the histological effect of the high-pressure pneumatic delivery system, specimens treated with various injection pressures were examined histologically.

Results : Subjective and objective assessments of skin laxity showed significant improvements 3 months after the treatment. Immediately after the procedure, the treated area showed noticeable tissue augmentation. No significant procedure-related adverse reactions were observed. Study limitations were the inclusion of relatively young-aged subjects and a small number of male subjects. Histologically, the specimens treated with the high-pressure pneumatic delivery system demonstrated numerous dermal vesicles composed of the injected fluid, which were located deeper in the dermis when a higher injection pressure was applied.

Conclusion : A high-pressure pneumatic delivery system proved to be safe and effective for skin laxity correction and resultant nasolabial folds in Asians.
KEYWORD
Face lifting, Needle-free injector, Needleless microjet device, Pressure
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